Circulating Natriuretic Peptide Concentrations in Hyperthyroid Cats

Menaut P., Connolly D.J., Volk A., et al.

The Journal of small animal practice, 2012. 53(12): p.673-8.


OBJECTIVES: To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment. METHODS: Serum natriuretic peptide concentration was measured in 61 hyperthyroid cats recruited from first-opinion clinics before and after treatment. RESULTS: Following successful treatment, total thyroxine, heart rate, systolic blood pressure and packed cell volume all decreased and bodyweight and creatinine concentrations increased. Furthermore, a significant (P < 0.001) decline in NT-proBNP concentration but not NT-proANP was identified. CLINICAL SIGNIFICANCE: Thyroid function has a modest but significant effect on NT-proBNP concentration. Thyroid status should be taken into account when interpreting NT-proBNP concentrations in cats.